Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

An immunodominant NP_105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.

Peng, Yanchun; Felce, Suet Ling; Dong, Danning; Penkava, Frank; Mentzer, Alexander J; Yao, Xuan; Liu, Guihai; Yin, Zixi; Chen, Ji-Li; Lu, Yongxu; Wellington, Dannielle; Wing, Peter A C; Dominey-Foy, Delaney C C; Jin, Chen; Wang, Wenbo; Hamid, Megat Abd; Fernandes, Ricardo A; Wang, Beibei; Fries, Anastasia; Zhuang, Xiaodong; Ashley, Neil; Rostron, Timothy; Waugh, Craig; Sopp, Paul; Hublitz, Philip; Beveridge, Ryan; Tan, Tiong Kit; Dold, Christina; Kwok, Andrew J; Rich-Griffin, Charlotte; Dejnirattisa, Wanwisa; Liu, Chang; Kurupati, Prathiba; Nassiri, Isar; Watson, Robert A; Tong, Orion; Taylor, Chelsea A; Kumar Sharma, Piyush; Sun, Bo; Curion, Fabiola; Revale, Santiago; Garner, Lucy C; Jansen, Kathrin; Ferreira, Ricardo C; Attar, Moustafa; Fry, Jeremy W; Russell, Rebecca A; Stauss, Hans J; James, William; Townsend, Alain.

Nat Immunol ; 23(1): 50-61, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34853448

2.

Forced Fox-P3 expression can improve the safety and antigen-specific function of engineered regulatory T cells.

McGovern, Jenny; Holler, Angelika; Thomas, Sharyn; Stauss, Hans J.

J Autoimmun ; 132: 102888, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36049437

3.

Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma.

Hotblack, Alastair; Holler, Angelika; Piapi, Alice; Ward, Sophie; Stauss, Hans J; Bennett, Clare L.

Mol Ther ; 26(6): 1471-1481, 2018 06 06.

Artigo em Inglês | MEDLINE | ID: mdl-29628306

4.

Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver.

Otano, Itziar; Escors, David; Schurich, Anna; Singh, Harsimran; Robertson, Francis; Davidson, Brian R; Fusai, Giuseppe; Vargas, Frederick A; Tan, Zhi M D; Aw, Jia Y J; Hansi, Navjyot; Kennedy, Patrick T F; Xue, Shao-An; Stauss, Hans J; Bertoletti, Antonio; Pavesi, Andrea; Maini, Mala K.

Mol Ther ; 26(11): 2553-2566, 2018 11 07.

Artigo em Inglês | MEDLINE | ID: mdl-30217730

5.

Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity.

Hou, Tie Zheng; Olbrich, Peter; Soto, Jose Manuel Lucena; Sanchez, Berta; Moreno, Paula Sanchez; Borte, Stephan; Stauss, Hans J; Burns, Siobhan O; Walker, Lucy S K; Pan-Hammarström, Qiang; Hammarström, Lennart; Sansom, David M; Neth, Olaf.

Clin Immunol ; 188: 94-102, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29305966

6.

Optimizing T-cell receptor gene therapy for hematologic malignancies.

Morris, Emma C; Stauss, Hans J.

Blood ; 127(26): 3305-11, 2016 06 30.

Artigo em Inglês | MEDLINE | ID: mdl-27207802

7.

Engineered T cells can fight malignant T cells.

Stauss, Hans J.

Blood ; 126(8): 927-8, 2015 Aug 20.

Artigo em Inglês | MEDLINE | ID: mdl-26294714

8.

CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.

Ghorashian, Sara; Veliça, Pedro; Chua, Ignatius; McNicol, Anne-Marie; Carpenter, Ben; Holler, Angelika; Nicholson, Emma; Ahmadi, Maryam; Zech, Mathias; Xue, Shao-An; Uckert, Wolfgang; Morris, Emma; Chakraverty, Ronjon; Stauss, Hans J.

J Immunol ; 194(3): 1080-9, 2015 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-25539815

9.

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.

Holler, Angelika; Zech, Mathias; Ghorashian, Sara; Pike, Rebecca; Hotblack, Alastair; Veliça, Pedro; Xue, Shao-An; Chakraverty, Ronjon; Morris, Emma C; Stauss, Hans J.

Haematologica ; 101(4): 482-90, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26802053

10.

Differences in systemic adaptive immunity contribute to the 'frequent exacerbator' COPD phenotype.

Geerdink, Jasper X; Simons, Sami O; Pike, Rebecca; Stauss, Hans J; Heijdra, Yvonne F; Hurst, John R.

Respir Res ; 17(1): 140, 2016 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-27793198

11.

Therapeutic potential of Tregs to treat rheumatoid arthritis.

Wright, Graham P; Stauss, Hans J; Ehrenstein, Michael R.

Semin Immunol ; 23(3): 195-201, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21880506

12.

No hiding place for BOB inside myeloma.

Stauss, Hans J.

Blood ; 129(10): 1236-1237, 2017 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-28280042

13.

Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction.

Simpson, Amy A; Mohammed, Fiyaz; Salim, Mahboob; Tranter, Amy; Rickinson, Alan B; Stauss, Hans J; Moss, Paul A H; Steven, Neil M; Willcox, Benjamin E.

Proc Natl Acad Sci U S A ; 108(52): 21176-81, 2011 Dec 27.

Artigo em Inglês | MEDLINE | ID: mdl-22160697

14.

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen.

Thomas, Sharyn; Xue, Shao-An; Bangham, Charles R M; Jakobsen, Bent K; Morris, Emma C; Stauss, Hans J.

Blood ; 118(2): 319-29, 2011 Jul 14.

Artigo em Inglês | MEDLINE | ID: mdl-21606483

15.

CD3 limits the efficacy of TCR gene therapy in vivo.

Ahmadi, Maryam; King, Judith W; Xue, Shao-An; Voisine, Cécile; Holler, Angelika; Wright, Graham P; Waxman, Jonathan; Morris, Emma; Stauss, Hans J.

Blood ; 118(13): 3528-37, 2011 Sep 29.

Artigo em Inglês | MEDLINE | ID: mdl-21750319

16.

Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination.

Pospori, Constandina; Xue, Shao-An; Holler, Angelika; Voisine, Cecile; Perro, Mario; King, Judith; Fallah-Arani, Farnaz; Flutter, Barry; Chakraverty, Ronjon; Stauss, Hans J; Morris, Emma C.

Blood ; 117(25): 6813-24, 2011 Jun 23.

Artigo em Inglês | MEDLINE | ID: mdl-21447831

17.

Synthetic Cell-Based Immunotherapies for Neurologic Diseases.

von Baumgarten, Louisa; Stauss, Hans J; Lünemann, Jan D.

Neurol Neuroimmunol Neuroinflamm ; 10(5)2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37385738

18.

Modifications outside CDR1, 2 and 3 of the TCR variable ß domain increase TCR expression and antigen-specific function.

Degirmencay, Abdullah; Thomas, Sharyn; Mohammed, Fiyaz; Willcox, Benjamin E; Stauss, Hans J.

Front Immunol ; 14: 1148890, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37122739

19.

Challenges in T cell receptor gene therapy.

Uttenthal, Benjamin J; Chua, Ignatius; Morris, Emma C; Stauss, Hans J.

J Gene Med ; 14(6): 386-99, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22610778

20.

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis.

Wright, Graham P; Notley, Clare A; Xue, Shao-An; Bendle, Gavin M; Holler, Angelika; Schumacher, Ton N; Ehrenstein, Michael R; Stauss, Hans J.

Proc Natl Acad Sci U S A ; 106(45): 19078-83, 2009 Nov 10.

Artigo em Inglês | MEDLINE | ID: mdl-19884493

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